Powder Scientist

Contracting – Walloon Brabant

Powder Scientist

Description de la fonction

As a “scienassionate” person and Powder Scientist you like to work in an environment where you can:

Participate to the development of new products and processes
Give directions from early development up to lifecycle management, from particle design up to final product
Work autonomous, well-organized and use your pro-active thinking skills
Be self-reflective on the gathered data
Use your creativity to develop new analytical methods or even develop new technology
Drive team spirit and encourage collaboration

As a “scienassionate” person and Powder Scientist you will contribute by:

Being a leader in powder characterization by leveraging Materials Science to drive overall Product Development in order to obtain the right drug for every patient
Guide the Product Development by connecting powder /particle insights with manufacturing technologies and overall product performance
Combine particle knowledge with crystallization science to optimize expected powder properties
Developing method and performing analyses on active ingredient, drug product and excipients in the field of powder characterization
Independently planning, conducting and interpreting experiments to determine the bulk powder and particle properties of raw materials, intermediates and final dosage forms, by mastering a number of characterization tools: laser diffraction (wet and dry method) and microscopy (optical and SEM) for particle size and shape measurements; gas pycnometry and fine solid displacement methods for true and envelope density determinations; physisorption for surface area quantification and porosimetry; powder rheometry to assess powder flow stability and strain-rate dependency; shear cell testing to measure powder flow functions and wall friction with application to hopper design; surface energy and wettability analyses via contact angle measurements (sessile drop, Washburn and Wilhelmy plate methods), standardized and customized methods to evaluate bulk/tapped density, powder compressibility, permeability, mechanical strengths of tablets and/or agglomerates, electrostatic charging, segregation, sticking and caking propensity; dynamic vapor sorption to assess powder hygroscopicity; differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) to understand the powder thermal behavior.
Performing chemical imaging on drug product or intermediates
Being the reference person in powder characterization and training colleagues
Applying QbD principles, multivariate analyses, and being in support of PAT development
Keeping track of literature and state of the art scientific practices, and implementing innovative solutions
Communicating with stakeholders and external partners (universities, centers of expertise,..)
Writing reports and give internal and external presentations

Profil

Master / PhD in chemistry, pharmaceutics, physics or engineering or equivalent experience, on powder characterization
Fluent in English
Ability to work at the interface
Able to combine multiple tasks and work simultaneously on different projects
Soft skills: entrepreneurship, motivated, enthusiastic, reliable, team player, good communication

Offre

Voiture d'entreprise

Jefferson Wells offers you a permanent contract as consultant with an attractive salary package and will give you access to trainings in technical matters and soft skills. We will be your career partner for each step along the way.

You’re interested in this job? We kindly invite you to apply. Do you have any questions? You can contact Caroline, Afficher l'adresse e-mail

Type de fonction :

Responsable de production

Secteur :

Sciences et recherche

Lieu de travail

Braine-l'Alleud

Exigences

Master (Licence, Université ou Enseignement Supérieur de Type Long) Français

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